The large number of cattle breeds which exist throughout the world represents an important resource for cattle breeding. However the very richness of this resource makes it impossible to compare a ll possible breeds and crosses in field experiments. Therefore a method of predicting the performance of different genotypes would be very useful.
According to the theory of quantitative genetics heterosis is simply the recovery of the inbreeding depression that has occurred in each breed since the breeds have been separated. The amount of inbreeding can be estimated from the gene frequencies at neutral loci and the inbreeding depression per per cent inbreeding is known from experiments on inbreeding.
In this paper we use published data on heterosis, inbreeding depression and gene frequencies to test the hypothesis that heterosis can be predicted in this way.

Michael E Goddard, A. M Ahmed

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 8. Symposia (2), , 377–381, 1982
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