Genetic progress from any selection regime is dependent upon four factors -- the heritability of the trait, the generation interval, the selection intensity, and the accuracy of selection. Embryo transfer is not expected to affect genetic change by reducing the additive genetic variation of a trait or by substantially reducing the generation interval. The greatest impact of embryo transfer will be on increasing selection intensity and accuracy. Embryo micromanipulation techniques will likely have their most immediate impact via embryo splitting. However, gene injection and other embryo engineering technologies may offer unique opportunities to alter the genetic constitution of an animal population.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XII. Biotechnology, selection experiments, parameter estimation, design of breeding systems, management of genetic resources., , 115–120, 1986
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