The level of reticuloendothelial (RE) activity in different genetic lines of chickens (Gallus domesticus) was evaluated by measuring the rate of in vivo clearance of colloidal carbon from the circulatory system. Several inbred lines, with inbreeding coefficients of 90-98%, were studied. Differences in RE activity among the inbred lines were highly significant {P< 0.05). The partially inbred Iowa State SI White Leghorn line was also studied. Chicks were produced in sublines from breeders selected for B blood group serotype, humoral immune response to the amino acid polymer, GAT, and response to Rous' sarcoma virus-induced (RSV) tumor development. Selection for response to RSV tumors, was significantly (P < 0.01) associated with level of RE activity. Sublines selected for ability to regress RSV tumors had a higher level of RE activity than those selected for tumor progression. These studies suggest that there is genetic control of reticuloendothelial activity in chickens which may be associated with the ability to genetically resist disease.

S. J Lamont

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XI. Genetics of reproduction, lactation, growth, adaptation, disease, and parasite resistance., , 643–647, 1986
Download Full PDF BibTEX Citation Endnote Citation Search the Proceedings

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.