A mathematical model is given which describes changes in gene frequency when there is directional selection on a trait under the control of a major gene and polygenes. It is used to show the effects of halothane testing and selection for leanness on the frequency of the halothane gene in pig stocks.

S. P Simpson

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XIII. Plenary lectures, molecular genetics and mapping, selection, prediction and estimation., , 269–272, 1990
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