The effect of continued selection on the efficiency of indirect selection relative to direct selection when a finite number of loci is considered was studied through Monte Carlo simulation. Computer results were compared with predictions based on an infinitesimal model. Theoretical expectations which account only for changes in relative efficiency due to the generation of linkage disequilibrium indicate a loss in efficiency of indirect selection when more than one cycle of selection is practised. Results of this study show that indirect selection is relatively less efficient when changes in gene frequencies are also considered. Caution should be taken in applying indirect selection procedure in practice
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XIII. Plenary lectures, molecular genetics and mapping, selection, prediction and estimation., , 265–268, 1990
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