Lines of mice divergently selected for 10 week body weight were investigated for the presence of segregating alleles with large effect on weight. It appears that the X chromosome may act as a "major gene" but whether due to single or multiple allelic differences has not yet been determined. The possible role of sex-linked genes in the response to selection is considered.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XIII. Plenary lectures, molecular genetics and mapping, selection, prediction and estimation., , 317–320, 1990
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