Selection experiments are carried out for many reasons. In some instances, the aim may be to develop genetically different lines for other purposes, such as physiological research, the progress of selection being of no inherent interest. In other cases, a selection experiment may be intended to help elucidate the genetical control of a particular character. A good deal of selection in mice is carried out for this motive, where the mouse is regarded as a model for the pig or other mammals, or is of interest for itself (McCarthy, 1980). However, a number of experiments have been conducted to evaluate quantitative genetic theory. Such experiments are particularly difficult, because the comparison of experimental results with theoretical predictions requires substantial replication to be used if the results are to be informative, since both prediction and empirical result are liable to errors of estimation.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume XIII. Plenary lectures, molecular genetics and mapping, selection, prediction and estimation., , 195–204, 1990
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