Under the usual mixed model of inheritance (Elston and Stewart, 1971; Morton and McLean, 1974), the exact likelihood cannot be calculated for large pedigrees, and likelihood analysis for large pedigrees is usually based on approximations of the likelihood. Fernando et al. (1994) proposed an alternative mixed model with a finitenumber of polygenic loci (FPMM), for which the likelihood can be efficiently calculated linkage analysis by maximum likelihood under an FPMM was compared with that under the usual mixed
model (UMM), where the likelihood under the UMM was approximated as described by Hasstedt (1982).
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 51–54, 1994
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