Replicates of mouse lines that had been selected within full-sib families for high or low epididymal fat pad weight (EF) holding body weight (BW) constant were crossed. After two generations of random mating, two replicates were sampled to reinitiate selection for the same criteria except that individual selection was used to increase the selection differentials. Realized heritabilities for index units based on high-fat, low-fat and divergent selection were 0.32 ± 0 .13 , 0.58 ± 0.002 and 0.41 ± 0.002, respectively. These estimates were not significantly different from those in the first phase of selection. In both phases of selection the restricted index designed to increase EF without changing BW was in agreement with expectation. In contrast, the index designed to decrease EF without changing BW did not agree with theory since BW increased and EF remained unchanged. There was, however, some replicate heterogeneity in response, suggesting that genetic drift may have played a role.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 19. Selection and quantitative genetics; growth; reproduction; lactation; fish; fiber; meat., , 32–35, 1994
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