Lines of mice have been divergently selected cm, and now differ five fold in, estimated fat content at 14 weeks of age. Individuals from each line were castrated or sham operated and subsequently given either exogenous testosterone or the appropriate control. Analysis of body weight, fat content and lean mass foiled to detect any interaction between these treatments and genetic background. It is concluded that testosterone metabolism has not contributed disproportionately to the response to artificial selection.

I. M Hastings, William G Hill

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 19. Selection and quantitative genetics; growth; reproduction; lactation; fish; fiber; meat., , 71–74, 1994
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