Estimates have been obtained of the variation deriving from mutation for 6-week body weight in the mouse from two experiments: (1) Long term selection was practised from an inbred base, which gave an estimate of the mutational heritability, h ^ (the ratio of the variance from mutation each generation to the environmental variance) of 0.6%; and (2) short term selection was practised from the cross of two long separated inbred sublines, which gave an estimate of h 0f 0.1%. Explanations for this difference and the information it gives us about the relation between effects of mutants on body size and fitness are discussed.

William G Hill, A. Caballero, P. D Keightley

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 19. Selection and quantitative genetics; growth; reproduction; lactation; fish; fiber; meat., , 67–70, 1994
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