Wool is a fibre made up of many proteins, which are arranged in several levels of structure. The number of proteins is difficult to estimate precisely, but it is probably 50-100. They can be divided into keratin intermediate filament proteins, designated type I and II, and keratin-associated proteins, within which eight families are presently recognised. The availability of genomic and cDNA probes has allowed the definition of Restriction Fragment Length Polymorphisms (RFLPs) and microsatellite markers for these genes. Polymorphisms have been found for genes in seven of the eight keratin-associated protein families. We give data which indicate that keratin gene markers might define some genetic variation in economically important characters of wooL
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 21. Gene mapping; polymorphisms; disease genetic markers; marker assisted selection; gene expression; transgenes; non-convention, , 113–116, 1994
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