Efficiency of detection of a QTL was compared between full-sib and half-sib designs in terms of the size of substitution effect of a QTL. Efficiency designated as t-value in full-sib design in compared to in half-sib design has become higher with the increase of size of the effect of a QTL. Efficiency in half-sib design with paternal family size and number of sire being 30 and 10, respectively was nearly the same as that of full-sib design under the number of sire, dam and offspring per dam being 10,5 and 8 respectively, as long as sire haplotype is fully identified from marker genotype of the offspring and under the condition that 10 % of the genetic variance in a trait whose heritability is 0.3 is explained by the QTL. In full-sib design, increasing the number of offspring per dam results in higher efficiency in detection of a QTL than increasing the number of dam when the product of number of dam and number of daughter is the same. T values in locating a QTL at position 0.1 treating marker distance as 1.0 are slightly higher than at position 0.

K. Togashi, N. Yamamoto, O. Sasaki

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 24: Sheep and goats (fibre); sheep and goats (meat and milk); poultry; horses; buffaloes., , 99–102, 1998
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