Efficiency of detection of a QTL was compared between full-sib and half-sib designs in terms of the size of substitution effect of a QTL. Efficiency designated as t-value in full-sib design in compared to in half-sib design has become higher with the increase of size of the effect of a QTL. Efficiency in half-sib design with paternal family size and number of sire being 30 and 10, respectively was nearly the same as that of full-sib design under the number of sire, dam and offspring per dam being 10,5 and 8 respectively, as long as sire haplotype is fully identified from marker genotype of the offspring and under the condition that 10 % of the genetic variance in a trait whose heritability is 0.3 is explained by the QTL. In full-sib design, increasing the number of offspring per dam results in higher efficiency in detection of a QTL than increasing the number of dam when the product of number of dam and number of daughter is the same. T values in locating a QTL at position 0.1 treating marker distance as 1.0 are slightly higher than at position 0.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 24: Sheep and goats (fibre); sheep and goats (meat and milk); poultry; horses; buffaloes., , 99–102, 1998
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