The prolactin receptor gene was investigated as a candidate gene for reproduction traits in five PIC lines consisting of Large White (2), Landrace, Duroc, and Large White/Meishan origin. Least square means for total number bom and number bom alive were calculated for each genotype in addition to an analysis of additive and dominance effects by line. The gene was significantly associated with total number bom and/or number bom alive in three of the lines tested. The magnitude ranged from 0.66 to greater than 1 pig per litter increase between homozygous genotypes and varied with background genetics. Also of interest was the lack of effect on average birth weight with the increase in litter size. This gene test has the potential to be a powerful tool when used in conjunction with traditional selection methods for some lines. Additional data is needed to confirm the significant effects seen in the three lines.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 27: Reproduction; fish breeding; genetics and the environment; genetics in agricultural systems; disease resistance; animal welf, , 15–18, 1998
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