Information from a scrapie epidemic in a closed INRA Romanov flock is presented. Performances, pedigree, histopathological diagnoses and Pm-P genotypes were recorded since the outbreak of the epidemic (in 1993). Major influence of the polymophisms at codons 154 and 171, as well as a side effect of polymorphism at codon 136 are shown. A possible relationship between gastrointestinal parasitism and scrapie is discussed.

Jean-Michel Elsen, J. VT Khang, F. Schelcher, Y. Amigues, F. Eychenne, J. P Poivey, F. Lantier, J. L Laplanche

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 27: Reproduction; fish breeding; genetics and the environment; genetics in agricultural systems; disease resistance; animal welf, , 269–272, 1998
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