Two pairs of chicken lines were developed from individual phenotypic selection for serum immunoglobulin M and G levels at 10 weeks of age. After three generations of selection, the lines were tested for their competences to graft-vs-host reaction (GVHR) and antibody response to brucella abortus (BA). Serum immunoglobulin M and G levels changed significantly (P<0.05) during the selection period. Splenomegaly indices, used to measure GVHR competence, differed significantly (P<0.05) between the high IgG (KG) and low IgG (LIG) lines. Total BA antibody titers also differed significantly (P<0.05) between the KG and LIG lines at 7 day postimmunization. The selected lines showed their divergence in T and B cell responses although the selection was conducted on the basis of serum immunoglobulin isotypes. 

N. Sarker, M. Tsudzuki, M. Nishibori, Y. Yamamoto

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 24: Sheep and goats (fibre); sheep and goats (meat and milk); poultry; horses; buffaloes., , 259–262, 1998
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