Trypanosomosis is endemic in 7 million km2 of sub-Saharan Africa and is one of the major constraints to livestock productivity, with 60 million cattle at constant risk of infection (FAO, 1991). The disease in cattle is largely due to infection with the tsetse fly-transmitted parasite Trypanosoma congolense and costs are estimated at over US$ 1.3 billion per annum (Kristianson et al., 1999). While most breeds of cattle are highly susceptible to trypanosomosis, some exhibit trypanotolerance, which is the ability to control levels of parasitaemia and anaemia, and to maintain productivity under challenge (Kemp and Teale, 1998). An F2 resource population derived from trypanotolerant Bos taurus N’Dama bulls and susceptible Bos indicus improved Kenya Boran cows, was developed at the International Laboratory for Research on Animal Diseases (now the International Livestock Research Institute) for mapping the quantitative trait loci (QTL) controlling trypanotolerance (Kemp and Teale, 1991 ; Kennedy, 1994).

O. Hanotte, A. Korol, M. Agaba, P. Nilsson, A. Gelhaus, R. Horstmann, Y. Sugimoto, S. Kemp, John P Gibson, Moshe Soller, A. Teale

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 2002. Session 13, , 13.06, 2002
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