Facial eczema (FE) is a liver disease caused by the mycotoxin sporidesmin. The disease affects sheep, cattle and deer, and costs the New Zealand livestock industries NZ$63-126M annually. Investigations into the genetic bases of FE resistance in sheep have included a genome QTL scan (Phua et al., 1998a) and candidate genes approach (Phua et al., 1998b). This report describes an alternative, but complementary, method using microarray technology to examine gene expression profiles in livers of FE resistant- and susceptible-line sheep in response to sporidesmin challenge. 

E. J Duncan, D. Hyndman, T. Wilson, M. P Thompson, S. H Phua

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume 2002. Session 13, , 13.17, 2002
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