The objective of this study was to detect association of single nucleotide polymorphisms (SNPs) in the lipoprotein lipase (LPL) gene and their haplotypes with fat deposition in chicken. The experimental population consisted of 15 intercross lines originated from four different breeds, White Leghorn, Silkies, CAU Brown, and White Plymouth Rock. A Total of 544 chickens were genotyped. Allele frequencies of three SNPs found in exon 7, 8 and 9 were significantly different across lines. Significant allele substitution effects in exon 7 and 8 were detected on inter-muscular fat width. As excessive fatness is recognized to be a major problem confronted by the poultry industry, further research efforts to assess possible associations of polymorphisms in the LPL gene with fatness are warranted.

Wang YaChun, Liu Rui, Yu Ying, Sun DongXiao, Flavio S Schenkel, Zhang Yuan

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume , , 07.30, 2006
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