Recently, a mutation in the regulatory region of the IGF2 gene has been identified to be the cause underlying the QTL effect on muscle growth and fat deposition. The aim of this study was to investigate a possible effect of this mutation on prolificacy and longevity. Results show that the wild type allele has a positive effect on live born, total born and weaned piglets per litter. This opens the possibility to use this imprinted QTN for different selection in sire and dam lines. Terminal sires should be homozygous for the lean allele to give uniform, lean slaughter pigs, while dam lines can benefit from a selection for the wild type allele because of its effect on prolificacy and longevity. Since the IGF2 gene is only paternally expressed, selection for the fatter allele in sow lines will not affect the carcass quality of slaughter pigs.

N. Buys, G. van den Abeele, A. Stinckens, J. Deley, M. Georges

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume , , 06.22, 2006
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