This paper discusses the strategies used by researchers and poultry breeding companies to determine the genetic bases for resistance to disease in poultry, and to identify biomarkers as tools that can be used for selection to enhance the natural variation in disease resistance that exists in poultry stocks. Genes and molecular markers can be identified by scanning the whole genome for either structural variation or differential gene expression associated with host resistance. Or, targeted study of genes based on comparative functional genomics can be used. There is a compelling need to identify genes and genomic regions associated with disease resistance, as well as to develop a basic understanding of the functional genomics involved. With this information, biomarkers can be identified for use in selection programs to genetically improve host resistance to disease in poultry.
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume , , 07.01, 2006
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