Abstract

ABSTRACT:Elevated pulmonary arterial pressure (PAP) is an indicator trait for bovine pulmonary hypertension. The objective of this study was to determine the genetic relationship between yearling PAP (YPAP), yearling weight (YW) and post-weaning gain (PWG). Heritability and genetic correlations were estimated with data from Angus heifers at Colorado State University Beef Improvement Center (CSU-BIC) using a multivariate animal model. A genome-wide association study was performed for each trait using univariate models. The estimated heritabilities of YPAP, YW and PWG were 0.22 ± 0.04, 0.43 ± 0.04 and 0.28 ± 0.04, respectively. Genetic correlations between YPAP and YW or PWG were low and positive (0.22 ± 0.04 and 0.04 ± 0.12, respectively). There were no genome windows associated with both YPAP and either weight trait. Selection for post-weaning growth should not lead to increased risk of high PAP in Angus heifers.

Xi Zeng, Rebecca Cockrum, Natalie F Berge, Joe M Neary, Franklyn B Garry, Timothy N Holt, Harvey D Blackburn, Scott E Speidel, Dorian J Garrick, Richard Mark Enns, Milton G Thomas

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Genetic Improvement Programs: Selection for harsh environments and management of animal genetic resources (Posters), , 428, 2014
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