SNP data on tumor necrosis factor-alpha (TNF-α) and TNF-R1 -1703T/C taken from 367 Red Steppe and Black and White cows bred in 3 Siberian farms were analyzed. The G allele frequencies in Red Steppe and Black-and-White population were found to be 0.510 and 0.526 respectively. It was estimated that milk and fat yield in first lactation per 305 lactation days of G/G Red Steppe cows was higher than in animals with А/А genotype. Milk and fat productivity were higher in G/G animals (farm 2) in comparison to heterozygotes for TNF-α -824 A/G SNP. However, it was dissimilarity among cows possessed different genotypes in farm 1. Milk yield was not associated with genotypes on TNF-R1 -1703T/C SNP. In fact, only cows with complex genotypes TNF-α -824 A/G and TNF-R1-1703T/C AA/TT and AA/CC at first lactation had a higher milk yield than AG/TT cows.

Valeriy L Petukhov

Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Genetic Improvement Programs: Selection using molecular information (Posters), , 487, 2014
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