The contribution of different functional SNP classes to genetic variation in global chicken populations D.K. Malomane1, C. Reimer1, S. Weigend2, A. Weigend2 & H. Simianer1 1University of Goettingen, Department of Animal Sciences, Animal Breeding and Genetics Group, Albrecht-Thaer-Weg 3, 37075 Goettingen, Germany email@example.com (Corresponding author) 2Friedrich-Loeffler-Institut, Institute of Farm Animal Genetics, Höltystraße 10, 31535 Neustadt, Germany To evaluate the contribution of different functional single nucleotide polymorphism (SNP) classes to genetic variation, we used a total 118,676 SNPs genotyped from 18 (3,231 individuals) global chicken breed types. We classified the SNPs into six genomic classes, estimated and compared allele frequency distributions and heterozygosity within breed types for the different SNP classes. There was no difference between the genic and non-genic classes in their contribution to genetic variation. Among the genic regions, allele frequency distributions showed that the missense sites were subjected to selection pressure. Overall the missense sites significantly contributed less to genetic variation than the other regions. Keywords: Chicken diversity, functional annotation, SNPs
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Electronic Poster Session - Species - Avian 1, , 620, 2018
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