In this paper, we present the prediction of deleterious variants in noncoding regions and protein-coding genes based on whole-genome sequence data of 673 pigs. Predicted sets are enriched for rare derived variants. The density of predicted deleterious variants across the genome correlates negatively with a proxy for recombination rate. The variants will be used for assessing the value of deleterious variants for increasing the accuracy of genomic selection, and for population genomics of and breeding to reduce deleterious load in pigs. Keywords: pig, deleterious load, sequencing, population genetics
Proceedings of the World Congress on Genetics Applied to Livestock Production, Volume Technologies - Gene Editing, , 153, 2018
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